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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDS5B All Species: 38.18
Human Site: S252 Identified Species: 70
UniProt: Q9NTI5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NTI5 NP_055847.1 1447 164667 S252 K T S I S D L S E H V F D L I
Chimpanzee Pan troglodytes XP_509623 1487 169149 S292 K T S I S D L S E H V F D L I
Rhesus Macaque Macaca mulatta XP_001118201 1528 173307 S332 K T S I S D L S E H V F D L I
Dog Lupus familis XP_543139 1623 183240 S427 K T S I S D L S E H V F D L I
Cat Felis silvestris
Mouse Mus musculus Q4VA53 1446 164401 S252 K T S I S D L S E H V F D L I
Rat Rattus norvegicus Q6TRW4 1447 164441 S252 K T S I S D L S E H V F D L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509617 1452 165101 S252 K T S I S D L S E H V F D L I
Chicken Gallus gallus Q5F3U9 1412 161007 S252 K T S I S D L S E H V F D L I
Frog Xenopus laevis Q5U241 1464 166906 S252 K T S I S D L S E H V F D L I
Zebra Danio Brachydanio rerio A1L1F4 1320 148940 S251 Q V L V M G K S S V S D L S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610719 1218 138870 S149 E I F Q D L F S T I F K I V N
Honey Bee Apis mellifera XP_623860 1203 137941 F135 V K S F N M C F E L E D C Q E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790621 1624 181368 A249 R S S T S D L A S H S Y E L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 94.3 88.4 N.A. 96.3 96.4 N.A. 94.4 91.4 84.4 63.9 N.A. 27.9 33.6 N.A. 40.3
Protein Similarity: 100 97.1 94.5 88.8 N.A. 97.7 97.7 N.A. 96.6 94.6 90.4 75.4 N.A. 46.5 52.3 N.A. 58.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 6.6 N.A. 6.6 13.3 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 20 N.A. 20 20 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 8 77 0 0 0 0 0 16 70 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 77 0 8 0 8 0 16 % E
% Phe: 0 0 8 8 0 0 8 8 0 0 8 70 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 77 0 0 0 0 0 % H
% Ile: 0 8 0 70 0 0 0 0 0 8 0 0 8 0 70 % I
% Lys: 70 8 0 0 0 0 8 0 0 0 0 8 0 0 0 % K
% Leu: 0 0 8 0 0 8 77 0 0 8 0 0 8 77 0 % L
% Met: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 85 0 77 0 0 85 16 0 16 0 0 8 0 % S
% Thr: 0 70 0 8 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 8 8 0 8 0 0 0 0 0 8 70 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _